Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Col1a1  collagen, type I, alpha 1   (Synonyms: Col1a-1, Cola1, Cola-1, Mov-13)
Results	Reference
1	J:128363 Arai KY, Nishiyama T, Developmental Changes in Extracellular Matrix Messenger RNAs in the Mouse Placenta During the Second Half of Pregnancy: Possible Factors Involved in the Regulation of Placental Extracellular Matrix Expression. Biol Reprod. 2007 Dec;77(6):923-33
1	J:119152 Arnold MA, Kim Y, Czubryt MP, Phan D, McAnally J, Qi X, Shelton JM, Richardson JA, Bassel-Duby R, Olson EN, MEF2C transcription factor controls chondrocyte hypertrophy and bone development. Dev Cell. 2007 Mar;12(3):377-89
1	J:75823 Aubin J, Lemieux M, Moreau J, Lapointe J, Jeannotte L, Cooperation of Hoxa5 and Pax1 Genes during Formation of the Pectoral Girdle. Dev Biol. 2002 Apr 1;244(1):96-113
1*	J:56413 Bachner D, Ahrens M, Betat N, Schroder D, Gross G, Developmental expression analysis of murine autotaxin (ATX). Mech Dev. 1999 Jun;84(1-2):121-5
1	J:128020 Barbosa AC, Funato N, Chapman S, McKee MD, Richardson JA, Olson EN, Yanagisawa H, Hand transcription factors cooperatively regulate development of the distal midline mesenchyme. Dev Biol. 2007 Oct 1;310(1):154-68
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1	J:198653 Blitz E, Sharir A, Akiyama H, Zelzer E, Tendon-bone attachment unit is formed modularly by a distinct pool of Scx- and Sox9-positive progenitors. Development. 2013 Jul;140(13):2680-90
1	J:156015 Blitz E, Viukov S, Sharir A, Shwartz Y, Galloway JL, Pryce BA, Johnson RL, Tabin CJ, Schweitzer R, Zelzer E, Bone ridge patterning during musculoskeletal assembly is mediated through SCX regulation of Bmp4 at the tendon-skeleton junction. Dev Cell. 2009 Dec;17(6):861-73
1*	J:32246 Cheah KS, Lau ET, Au PK, Tam PP, Expression of the mouse alpha 1(II) collagen gene is not restricted to cartilage during development. Development. 1991 Apr;111(4):945-53
1*	J:89221 Dacquin R, Mee PJ, Kawaguchi J, Olmsted-Davis EA, Gallagher JA, Nichols J, Lee K, Karsenty G, Smith A, Knock-in of nuclear localised beta-galactosidase reveals that the tyrosine phosphatase Ptprv is specifically expressed in cells of the bone collar. Dev Dyn. 2004 Apr;229(4):826-34
1	J:310908 Deng J, Wang S, Li N, Chen X, Wang B, Liu H, Zhu L, Cong W, Xiao J, Liu C, Noggin Overexpression Impairs the Development of Muscles, Tendons, and Aponeurosis in Soft Palates by Disrupting BMP-Smad and Shh-Gli1 Signaling. Front Cell Dev Biol. 2021;9:711334
1	J:222247 Duan X, Murata Y, Liu Y, Nicolae C, Olsen BR, Berendsen AD, Vegfa regulates perichondrial vascularity and osteoblast differentiation in bone development. Development. 2015 Jun 1;142(11):1984-91
1	J:295760 Felsenthal N, Rubin S, Stern T, Krief S, Pal D, Pryce BA, Schweitzer R, Zelzer E, Development of migrating tendon-bone attachments involves replacement of progenitor populations. Development. 2018 Dec 18;145(24):dev165381
1*	J:35138 Galera P, Park RW, Ducy P, Mattei MG, Karsenty G, c-Krox binds to several sites in the promoter of both mouse type I collagen genes. Structure/function study and developmental expression analysis. J Biol Chem. 1996 Aug 30;271(35):21331-9
1	J:98430 Glass DA 2nd, Bialek P, Ahn JD, Starbuck M, Patel MS, Clevers H, Taketo MM, Long F, McMahon AP, Lang RA, Karsenty G, Canonical wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell. 2005 May;8(5):751-64
1	J:272582 Gupta K, Levinsohn J, Linderman G, Chen D, Sun TY, Dong D, Taketo MM, Bosenberg M, Kluger Y, Choate K, Myung P, Single-Cell Analysis Reveals a Hair Follicle Dermal Niche Molecular Differentiation Trajectory that Begins Prior to Morphogenesis. Dev Cell. 2019 Jan 7;48(1):17-31.e6
1	J:114686 Hinoi E, Bialek P, Chen YT, Rached MT, Groner Y, Behringer RR, Ornitz DM, Karsenty G, Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium. Genes Dev. 2006 Nov 1;20(21):2937-42
1*	J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
1	J:94274 Hu H, Hilton MJ, Tu X, Yu K, Ornitz DM, Long F, Sequential roles of Hedgehog and Wnt signaling in osteoblast development. Development. 2005 Jan;132(1):49-60
1*	J:42584 Huang LF, Fukai N, Selby PB, Olsen BR, Mundlos S, Mouse clavicular development: analysis of wild-type and cleidocranial dysplasia mutant mice. Dev Dyn. 1997 Sep;210(1):33-40
1*	J:171508 Ikegami D, Akiyama H, Suzuki A, Nakamura T, Nakano T, Yoshikawa H, Tsumaki N, Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways. Development. 2011 Apr;138(8):1507-19
1*	J:156020 Kanamoto T, Mizuhashi K, Terada K, Minami T, Yoshikawa H, Furukawa T, Isolation and characterization of a novel plasma membrane protein, osteoblast induction factor (obif), associated with osteoblast differentiation. BMC Dev Biol. 2009;9:70
1*	J:53540 Kim IS, Otto F, Zabel B, Mundlos S, Regulation of chondrocyte differentiation by Cbfa1. Mech Dev. 1999 Feb;80(2):159-70
1	J:175747 Liu W, Watson SS, Lan Y, Keene DR, Ovitt CE, Liu H, Schweitzer R, Jiang R, The atypical homeodomain transcription factor Mohawk controls tendon morphogenesis. Mol Cell Biol. 2010 Oct;30(20):4797-807
1	J:152843 Luo J, Zhou W, Zhou X, Li D, Weng J, Yi Z, Cho SG, Li C, Yi T, Wu X, Li XY, de Crombrugghe B, Hook M, Liu M, Regulation of bone formation and remodeling by G-protein-coupled receptor 48. Development. 2009 Aug;136(16):2747-56
1	J:197791 Masago Y, Hosoya A, Kawasaki K, Kawano S, Nasu A, Toguchida J, Fujita K, Nakamura H, Kondoh G, Nagata K, The molecular chaperone Hsp47 is essential for cartilage and endochondral bone formation. J Cell Sci. 2012 Mar 1;125(Pt 5):1118-28
1	J:182340 Michikami I, Fukushi T, Tanaka M, Egusa H, Maeda Y, Ooshima T, Wakisaka S, Abe M, Kruppel-like factor 4 regulates membranous and endochondral ossification. Exp Cell Res. 2012 Feb 15;318(4):311-25
1	J:149225 Miclea RL, Karperien M, Bosch CA, van der Horst G, van der Valk MA, Kobayashi T, Kronenberg HM, Rawadi G, Akcakaya P, Lowik CW, Fodde R, Wit JM, Robanus-Maandag EC, Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors. BMC Dev Biol. 2009;9:26
1*	J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109
1*	J:241850 Naiman N, Fujioka K, Fujino M, Valerius MT, Potter SS, McMahon AP, Kobayashi A, Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Dev Cell. 2017 May 22;41(4):349-365.e3
1*	J:31239 Niederreither K, D'Souza R, Metsaranta M, Eberspaecher H, Toman PD, Vuorio E, De Crombrugghe B, Coordinate patterns of expression of type I and III collagens during mouse development. Matrix Biol. 1995 Dec;14(9):705-13
1*	J:74179 Nikaido T, Yokoya S, Mori T, Hagino S, Iseki K, Zhang Y, Takeuchi M, Takaki H, Kikuchi S, Wanaka A, Expression of the novel transcription factor OASIS, which belongs to the CREB/ATF family, in mouse embryo with special reference to bone development. Histochem Cell Biol. 2001 Aug;116(2):141-8
1	J:140208 Oka K, Oka S, Hosokawa R, Bringas P Jr, Brockhoff HC 2nd, Nonaka K, Chai Y, TGF-beta mediated Dlx5 signaling plays a crucial role in osteo-chondroprogenitor cell lineage determination during mandible development. Dev Biol. 2008 Sep 15;321(2):303-9
1	J:239772 Parada C, Han D, Grimaldi A, Sarrion P, Park SS, Pelikan R, Sanchez-Lara PA, Chai Y, Disruption of the ERK/MAPK pathway in neural crest cells as a potential cause of Pierre Robin sequence. Development. 2015 Nov 01;142(21):3734-45
1*	J:340391 Pina JO, Raju R, Roth DM, Winchester EW, Chattaraj P, Kidwai F, Faucz FR, Iben J, Mitra A, Campbell K, Fridell G, Esnault C, Cotney JL, Dale RK, D'Souza RN, Multimodal spatiotemporal transcriptomic resolution of embryonic palate osteogenesis. Nat Commun. 2023 Sep 14;14(1):5687
1	J:343286 Queen R, Crosier M, Eley L, Kerwin J, Turner JE, Yu J, Alqahtani A, Dhanaseelan T, Overman L, Soetjoadi H, Baldock R, Coxhead J, Boczonadi V, Laude A, Cockell SJ, Kane MA, Lisgo S, Henderson DJ, Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves. PLoS Genet. 2023 Nov;19(11):e1010777
1*	J:320343 Randilini A, Fujikawa K, Shibata S, An in situ hybridization study of decorin and biglycan mRNA in mouse osteoblasts in vivo. Anat Sci Int. 2021 Mar;96(2):265-272
1*	J:116229 Roulet M, Ruggiero F, Karsenty G, Leguellec D, A comprehensive study of the spatial and temporal expression of the col5a1 gene in mouse embryos: a clue for understanding collagen V function in developing connective tissues. Cell Tissue Res. 2007 Feb;327(2):323-32
1	J:105169 Sasaki T, Ito Y, Bringas P Jr, Chou S, Urata MM, Slavkin H, Chai Y, TGF{beta}-mediated FGF signaling is crucial for regulating cranial neural crest cell proliferation during frontal bone development. Development. 2006 Jan;133(2):371-81
1	J:142447 Sato S, Kimura A, Ozdemir J, Asou Y, Miyazaki M, Jinno T, Ae K, Liu X, Osaki M, Takeuchi Y, Fukumoto S, Kawaguchi H, Haro H, Shinomiya K, Karsenty G, Takeda S, The distinct role of the Runx proteins in chondrocyte differentiation and intervertebral disc degeneration: Findings in murine models and in human disease. Arthritis Rheum. 2008 Sep;58(9):2764-75
1*	J:143455 Settembre C, Arteaga-Solis E, McKee MD, de Pablo R, Al Awqati Q, Ballabio A, Karsenty G, Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of FGF signaling during endochondral ossification. Genes Dev. 2008 Oct 1;22(19):2645-50
1	J:235082 Shimazu J, Wei J, Karsenty G, Smurf1 Inhibits Osteoblast Differentiation, Bone Formation, and Glucose Homeostasis through Serine 148. Cell Rep. 2016 Apr 5;15(1):27-35
1	J:187998 Shung CY, Ota S, Zhou ZQ, Keene DR, Hurlin PJ, Disruption of a Sox9-beta-catenin circuit by mutant Fgfr3 in thanatophoric dysplasia type II. Hum Mol Genet. 2012 Nov 1;21(21):4628-44
1*	J:76263 Stricker S, Fundele R, Vortkamp A, Mundlos S, Role of Runx genes in chondrocyte differentiation. Dev Biol. 2002 May 1;245(1):95-108
1	J:287435 Sun P, He L, Jia K, Yue Z, Li S, Jin Y, Li Z, Siwko S, Xue F, Su J, Liu M, Luo J, Regulation of body length and bone mass by Gpr126/Adgrg6. Sci Adv. 2020 Mar;6(12):eaaz0368
1*	J:67784 Takeda S, Bonnamy JP, Owen MJ, Ducy P, Karsenty G, Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice. Genes Dev. 2001 Feb 15;15(4):467-81
1*	J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76
1*	J:284147 Velecela V, Torres-Cano A, Garcia-Melero A, Ramiro-Pareta M, Muller-Sanchez C, Segarra-Mondejar M, Chau YY, Campos-Bonilla B, Reina M, Soriano FX, Hastie ND, Martinez FO, Martinez-Estrada OM, Epicardial cell shape and maturation are regulated by Wt1 via transcriptional control of Bmp4. Development. 2019 Oct 17;146(20):dev178723
1	J:317065 Wan L, Zou W, Gao D, Inuzuka H, Fukushima H, Berg AH, Drapp R, Shaik S, Hu D, Lester C, Eguren M, Malumbres M, Glimcher LH, Wei W, Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1. Mol Cell. 2011 Dec 9;44(5):721-33
1	J:223511 Wei J, Shimazu J, Makinistoglu MP, Maurizi A, Kajimura D, Zong H, Takarada T, Lezaki T, Pessin JE, Hinoi E, Karsenty G, Glucose Uptake and Runx2 Synergize to Orchestrate Osteoblast Differentiation and Bone Formation. Cell. 2015 Jun 18;161(7):1576-91
1*	J:28954 Yoshioka H, Iyama K, Inoguchi K, Khaleduzzaman M, Ninomiya Y, Ramirez F, Developmental pattern of expression of the mouse alpha 1 (XI) collagen gene (Col11a1). Dev Dyn. 1995 Sep;204(1):41-7
1	J:238902 Zhou G, Jiang X, Zhang H, Lu Y, Liu A, Ma X, Yang G, Yang R, Shen H, Zheng J, Hu Y, Yang X, Zhang WJ, Xie Z, Zbtb20 regulates the terminal differentiation of hypertrophic chondrocytes via repression of Sox9. Development. 2015 Jan 15;142(2):385-93
1	J:219364 Zhou ZQ, Ota S, Deng C, Akiyama H, Hurlin PJ, Mutant activated FGFR3 impairs endochondral bone growth by preventing SOX9 downregulation in differentiating chondrocytes. Hum Mol Genet. 2015 Mar 15;24(6):1764-73
1	J:243660 Zhu XJ, Yuan X, Wang M, Fang Y, Liu Y, Zhang X, Yang X, Li Y, Li J, Li F, Dai ZM, Qiu M, Zhang Z, Zhang Z, A Wnt/Notch/Pax7 signaling network supports tissue integrity in tongue development. J Biol Chem. 2017 Jun 02;292(22):9409-9419